Intraindividual comparison of [177Lu]Lu-DOTA-EB-TATE and [177Lu]Lu-DOTA-TOC
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چکیده
منابع مشابه
Comparison of receptor affinity of natSc-DOTA-TATE versus natGa-DOTA-TATE.
BACKGROUND 44Sc as a positron emitter can be an interesting alternative to 68Ga (T½=67.71 min) due to its longer half-life (T½=3.97 h). Moreover, the b-emitter 47Sc can be used for therapy when attached to the same biomolecule vectors. DOTA as a chelating agent has been proven suitable for the radiolabelling of peptides recognising tumour cell receptors in vivo with M3+ radiometals. DOTA-deriva...
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OBJECTIVE In-111 ((111)In)-labeled octreotide has been clinically used for imaging somatostatin receptor-positive tumors, and radiolabeled octreotide analogs for positron emission tomography (PET) have been developed. Cu-64 ((64)Cu; half-life, 12.7 h) is an attractive radionuclide for PET imaging and is produced with high specific activity using a small biomedical cyclotron. The aim of this stu...
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A 65-year-old female patient who had been operated 20 years ago for parathyroid adenoma presented with left arm mass suspicious for metastatic lesion. First she was referred for bone scintigraphy for evaluation of osteoblastic activity of this lesion and examining other possible lesions at the skeleton. 99mTcMDP whole-body bone scan revealed multiple increased tracer uptake at the skeletal syst...
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Georgios Z. Papadakisa, Samira M. Sadowskib,c, Ulas Bagcid, Corina Milloe Warren Grant Magnuson Clinical Center (CC), National Institutes of Health (NIH), Bethesda, USA; National Cancer Institute, National Institutes of Health, Bethesda, USA; University Hospitals of Geneva, Geneva, Switzerland; University of Central Florida, Orlando, USA; Clinical Center, National Institutes of Health, Bethesda...
متن کاملCorrelation of Somatostatin Receptor-2 Expression with Gallium-68-DOTA-TATE Uptake in Neuroblastoma Xenograft Models
Peptide-receptor imaging and therapy with radiolabeled somatostatin analogs such as 68Ga-DOTA-TATE and 177Lu-DOTA-TATE have become an effective treatment option for SSTR-positive neuroendocrine tumors. The purpose of this study was to evaluate the correlation of somatostatin receptor-2 (SSTR2) expression with 68Ga-DOTA-TATE uptake and 177Lu-DOTA-TATE therapy in neuroblastoma (NB) xenograft mode...
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ژورنال
عنوان ژورنال: European Journal of Nuclear Medicine and Molecular Imaging
سال: 2021
ISSN: 1619-7070,1619-7089
DOI: 10.1007/s00259-020-05177-z